About Us

About BiotechPack

Beijing BiotechPack Scientific Co., Ltd. (abbreviated as BTP) was established in 2015. It is engaged in the characterization of biological products based on biological mass spectrometry, mass spectrometry analysis of macromolecules (including proteins, peptides, metabolites), and detection services for small molecules.

• The company adopts the ISO9001 quality control system, and professionally provides CRO testing and analysis services based on mass spectrometry;
• Recognized by the national CNAS laboratory, it provides drug quality research services in compliance with global pharmaceutical regulations;
• The business scope covers proteomics, peptidomics, metabolomics, biopharmaceutical characterization, single-cell analysis, single-cell mass spectrometry flow cytometry, bioinformatics cloud analysis, and multi-omics mass spectrometry integrated analysis, etc.;
• Seven quality control testing platforms to meet your one-stop service needs;
• Serving over 3,000 enterprises and chosen by over 10,000 customers;
• Committed to providing you with high-quality biological mass spectrometry analysis services!

 

BTP's dual quality control (CNAS and ISO9001) testing platforms include: physical and chemical analysis platform for biological products, structural characterization analysis platform for biological products, immunopeptide and immunology testing platform, single-cell analysis platform, proteomics and metabolomics analysis platform, protein sequencing platform, and data cloud platform. The company has independent mass spectrometry laboratories, chromatography laboratories, cell culture rooms, and immunology laboratories, as well as high-resolution mass spectrometers and high-performance liquid chromatography. It has established cooperative relationships with domestic and foreign drug R&D enterprises and universities such as Harvard University and Peking University, assisting clients in publishing multiple articles in high-level journals, including Cell.

 

Since the development of the company's independent testing platform, it has covered multiple omics testing platforms such as proteomics, metabolomics, biological products, and bioinformatics analysis. It has accumulated rich practical experience, and with professional technology and quality service, its clients include renowned institutions such as Peking University, Tsinghua University, and the Chinese Academy of Sciences, and it has established cooperative relationships with many domestic and foreign drug R&D enterprises. The company is committed to providing efficient, accurate, and cost-effective protein (omics) research technology packages for various scientific research institutions, enterprises, and organizations, helping clients achieve breakthroughs in basic research, molecular diagnostics, and other life science research fields, contributing to the development of life sciences.

 

BiotechPack's Seven Quality Control Testing Platforms

 

 

1.Biological Products Physical and Chemical Analysis Platform:This platform is equipped with multiple high-performance liquid chromatographs (Agilent & Waters), capillary electrophoresis instruments (Beckman), circular dichroism spectrometers (Jasco), infrared spectrometers (Thermo), micro differential scanning calorimeters (Malvern Panalytical), gel imaging systems (ProteinSimple), multifunctional enzyme labelers (Molecular Devices), two-dimensional electrophoresis instruments (GE), and inductively coupled plasma mass spectrometers (Thermo), enabling purity analysis of biopharmaceuticals, amino acid composition and extinction coefficient analysis, charge heterogeneity and isoelectric point analysis, advanced structure analysis, process/product impurity analysis, etc.

 

2.Biological Products Structural Characterization Analysis Platform:This platform is equipped with automated sample preparation systems (Intavis), HDX hydrogen-deuterium exchange systems (Trajan), Edman degradation sequencers (Shimadzu), and ultra-high performance liquid chromatography high-resolution mass spectrometry (AB Sciex & Thermo), enabling molecular weight detection of protein/nucleic acid drugs, sequence analysis of protein/nucleic acid drugs, N-terminal/C-terminal sequence analysis of protein drugs, peptide mapping analysis of protein drugs, glycosylation analysis of protein drugs, disulfide bond analysis of protein products, antibody/antigen binding site analysis, small molecule and target protein binding site analysis, and mRNA drug capping and tailing analysis, etc.

 

3.Immunopeptide and Immunology Testing Platform:This platform is equipped with highly specific human and mouse MHC-I and MHC-II molecule antibody libraries, ultra-high performance liquid chromatography high-resolution mass spectrometry (Orbitrap Eclipse), ELISPOT analyzers (CTL), HLA epitope binding prediction algorithm platforms based on deep learning networks, and biopharmaceutical antigen-presenting peptide analysis platforms. Mass spectrometry-based MHC-I immunopeptidomics analysis combined with epitope prediction algorithms enables screening of tumor neoantigens, immunogenicity verification of new antigens is achieved based on the immunology testing platform, T cell screening and TCR sequencing are achieved in combination with the single-cell analysis platform, and MHC-II biopharmaceutical antigen-presenting peptide analysis based on mass spectrometry enables identification of immunogenic source fragments of protein drugs.

 

4.Single-Cell Analysis Platform:This platform is equipped with single-cell sequencers (10x Genomics) and mass cytometry analyzers (Fluidigm Helios), enabling analysis of individual cells at the mRNA and protein levels. This platform plays an important role in antibody discovery, research on disease mechanisms and drug action mechanisms, PK/PD studies of cell therapy products, and drug discovery and screening. The single-cell analysis platform can be applied in the development and optimization of biological products, quality control of biological products, cell therapy, drug action mechanism research, and personalized treatment.

 

5.Proteomics and Metabolomics Analysis Platform:This platform is equipped with complete sample preparation equipment (including cell disruptors, tissue homogenizers, tissue grinders, etc.), highly specific protein phosphorylation/tyrosine phosphorylation/glycosylation/ubiquitination enrichment platforms, and ultra-high performance liquid chromatography high-resolution mass spectrometry (Orbitrap Exploris 240 & Orbitrap Exploris 480 With FAIMS Pro). It enables efficient extraction of proteins and metabolites at the omics level, efficient enrichment of specific modified peptides at the omics level, identification and relative quantification of proteins and metabolites at the omics level (3D & 4D), and absolute quantification analysis of specific proteins and metabolites at the omics level.

 

6.Protein Sequencing Platform:This platform is equipped with protein N-terminal sequence analyzers (Shimadzu), ultra-high performance liquid chromatography high-resolution mass spectrometry (Vanquish Neo-Orbitrap Fusion Lumos With ETD), and optimized de novo protein sequencing algorithm platforms. The protein N-terminal sequence analyzer provides accurate starting points for protein N-termini, and the ETD module on the mass spectrometry platform enables accurate differentiation of I and L within proteins, thereby allowing precise determination of the amino acid sequence of any protein/antibody. In conjunction with the physical and chemical analysis and structural characterization platforms for biological products and biopharmaceuticals, it enables analysis of the physicochemical properties and structural characterization of each sequenced protein/antibody. In conjunction with the single-cell analysis platform, it enables polyclonal antibody sequencing analysis.

 

7.Data Cloud Platform:Data analysis----result presentation----report delivery----project data storage and backup services.

 

Contact Us:

Scientific Research Service Phone:010-67869385
Mobile:152-0137-7680
WeChat: 13717565893
QQ: 3158880571
Website: www.biotech-pack.com
Email: info@biotech-pack.com
Address: No. 88 Kechuang Sixth Street, Economic and Technological Development Zone, Beijing

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