Microorganisms have been present on Earth for at least 3.8 billion years, occupying almost every corner of the biosphere. The diversity of their metabolic capabilities and forms is unmatched by other organisms on Earth. Compared to eukaryotes, microorganisms have smaller genomes, and the amount of data obtained from genomics, transcriptomics, and proteomics is relatively limited. However, metabolomics research is not affected by this limitation (about 20,000 microbial metabolites have been elucidated), allowing for a comprehensive understanding of microbial physiological functions. These factors give metabolomics its unique advantages in microbial research. As a new member of the functional genomics research technology family, metabolomics reflects the response of cells to environmental and genetic changes through comprehensive analysis of microbial cell metabolites. Since metabolomics more closely reflects cellular function, it is considered an excellent tool for studying microbial cell functions. Additionally, the small size, simple structure, relatively easy cultivation conditions, and the ability to obtain large quantities of cultures in a short time for most microorganisms make it easy to link metabolic processes with cell functions or phenotypes. The data obtained from metabolomics is distinctly different from genomics (what could happen), transcriptomics (what can happen), and proteomics (what is based on happening), as it reflects what has already occurred in the cell.
Baitaipike offers a one-stop service for microbial metabolomics. You only need to send us your experimental objectives and samples, and we will handle all subsequent experiments. Baitaipike has established metabolomics research platforms for primary and secondary microbial metabolites using Thermo's Q Exactive and AB's Q TOF 5600 mass spectrometers. Depending on your experimental objectives, we use different sample processing methods to efficiently extract microbial metabolites for analysis, effectively answering your biological questions while enhancing the identification and quantification accuracy of metabolites.
Research Route
Microbial Metabolomics Research Route
About Samples
To comprehensively analyze metabolites, sample extraction methods should meet the following requirements: extract as many metabolites as possible; be unbiased; not destroy or alter the physical or chemical properties of metabolites.
During the actual experiment, we will conduct a preliminary test on your experimental samples. In the preliminary test, we use various extraction methods for metabolites and analyze the samples obtained from each method using mass spectrometry. The raw data from different extraction methods is then subjected to in-depth bioinformatics analysis. By matching the identified metabolites with those you are interested in, we choose one or two suitable extraction methods for subsequent formal batch sample processing and analysis based on the matching results.
Bilingual Project Report
In the technical report, Baitaipike Biotechnology will provide you with a detailed bilingual (Chinese/English) technical report, including:
1. Experimental Procedures (Chinese and English)
2. Relevant Mass Spectrometry Parameters (Chinese and English)
3. Mass Spectrometry Images
4. Raw Data
5. Metabolomics Analysis Results
Microbial Metabolomics One-stop Service
You only need to place an order and send samples
Baitaipike One-stop Service Completion: Sample Processing - Instrumental Analysis - Data Analysis - Project Report
