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SEC-based Molecular Size Variation Analysis

Molecular size variation is a key factor affecting the properties of biological macromolecules such as proteins, antibodies, and polypeptides, playing a crucial role especially in drug development and bioproduct manufacturing. SizeExclusion Chromatography (Size Exclusion Chromatography, SEC), also known as Gel Permeation Chromatography (GPC), is a chromatographic technique for separating compounds based on molecular size. This technique utilizes the size exclusion effect of the pore size in the column packing material, allowing molecules of different sizes to pass through the chromatographic column at different speeds, thereby achieving separation.,by comparing the elution order of standard proteins of known sizes with the sample, the relative molecular size of the sample can be inferred.

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BTPMolecular Size Variation Analysis Based on SEC

Based onSECformolecular size variation analysiscanprovide information aboutthe size, molecular weight, and size distribution ofeach molecule in the sample,and has become an indispensable tool in fields such as drug quality control, vaccine development, and enzyme activity research.Biotyech BioTech (BTP)has dual quality system certification from CNAS/ISO9001; the companyhas established an efficientmolecular size variation analysisplatform based on advanced SEC systems and high-sensitivity detectors, providing comprehensive and accurate SEC molecular size variation analysis services for you. Combined with professional data processing and interpretation, our analysis platform is designed to meet your quality requirements for protein or polypeptide products during the research and production process. Whether it's high molecular weight polymers, medium molecular weight target proteins, or low molecular weight degradation products, BTP can provide you with comprehensive solutions and data support in a short time.


Bilingual Project Report in Chinese/English

In the technical report, Biotyech will provide you with a detailed bilingual technical report in Chinese and English, including:

1. Experimental procedures (Chinese/English)
2. Relevantexperimentalparameters (Chinese/English)
3. Detailed information on the molecular size variation analysis based on SEC
4. Electrophoresisimages
5. Raw data

One-stop Service for Molecular Size Variation Analysis Based on SECOne-stop Service

You only need to place an order and send the samples
Biotyech's one-stop service completes: sample processing - instrument analysis - data analysis - project report

Related Services

Protein Purity Analysis (Size Exclusion/Reverse Phase Chromatography)

Product-related Impurity Analysis

Other Process-related Impurity Analysis

Impurity Analysis

Molecular Weight Determination
Protein Molecular Weight Determination

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