Charge Heterogeneity Analysis Based on Ion Chromatography

In the biopharmaceutical process, especially for protein and antibody drugs, charge heterogeneity analysis is crucial for understanding and controlling the quality of the production process.The interaction between molecules with different charge states may affect the bioactivity, immunogenicity, half-life, and charge stability of the drug, thereby influencing the drug's efficacy, stability, and safety.Ion Chromatography (Ion Chromatography,IC) is a widely used technique for analyzing the charge heterogeneity of biomolecules.It utilizes the electrostatic interactions between charged molecules and ion exchange resins to achieve the separation of molecules with different charge states, in order todistinguish and measure thecharge characteristicsof different particles in the sample.It provides a key tool for the development and quality control of pharmaceutical vaccines, antibody drugs, enzyme preparations, and other protein-based drugs.Key tool.

 

BTP's ion chromatography-based charge heterogeneity analysis

 

Bio-Tech Pack (BTP)(BTP)has been certified by both CNAS and ISO9001 quality systems.The companyutilizes advanced ion exchange chromatographsin combination withprofessional data analysis methods,to develop an efficient ion chromatography-based charge heterogeneity analysis platform,providing you with precise and comprehensive charge heterogeneity analysis services, including routine charge heterogeneity analysis and in-depth charge analysis, such as qualitative and quantitative analysis of charge variants, component analysis of charge heterogeneity, and evaluation of the impact of charge state on drug stability and activity, offeringcomprehensive support in drug development, production, and quality control.,Feel free to contact us for a free consultation to learn more!

Bilingual Project Report (Chinese/English)

In the technical report, Bio-Tech Pack will provide you with a detailed bilingual technical report in Chinese and English, including:

1. Experiment steps (Chinese/English)
2. Relatedchromatographicparameters (Chinese/English)
3. Detailed information on ion chromatography-based charge heterogeneity analysis
4. Chromatographicimages
5. Raw data

One-stop service for ion chromatography-based charge heterogeneity analysisYou only need to place an order and send your samples

Bio-Tech Pack provides a one-stop service: sample processing, on-machine analysis, data analysis, project report
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