HCP Qualitative Identification and Relative Quantitative Analysis
Host Cell Proteins (HCP) are proteins expressed by production cells during the manufacturing process of biopharmaceuticals and may remain in the final product. HCPs are a critical quality attribute that needs strict control in the development and production of biopharmaceuticals, especially recombinant protein drugs., theirpresence not only potentially affects the purity and stability of the drug but also may causeadverseimmune reactions in the body. Therefore, qualitative identification and relative quantitative analysis of HCPs are essential steps in drug development and quality control. Qualitative identification of HCPs is primarily used to confirm the presence of HCPs in biopharmaceutical samples,enabling accurate identification and differentiation of various HCPs in complex drug samples. Relative quantitative analysis is a method to evaluate the relative abundance of HCPs in samples, calculating their relative abundance in the sample by comparing the signal intensity of HCPs, thus assessing the quality and safety of the drug.
BTP BiosciencesHCP Qualitative Identification and Relative Quantitative AnalysisProcess
BTP Biosciences(BTP)is certified byCNAS/ISO9001 dual quality system; the companybased onThermocompany's latestObitrap Fusion Lumosmass spectrometer combined withNano-LCnano-liquid chromatography technology,establishesan HCP qualitative identification and relative quantitative analysis platform, which can identify specific information such as the name, pI, and MW of each HCP in biopharmaceuticals. By using PRM data acquisition, it allows for the measurement of relative content of certain specific HCPs (ranging from several to dozens), providing a powerful tool for screening high-risk HCPs and optimizing processes.BTP's expert team has years of experience in bioanalysis and drug development, offering your projecta free customizedpersonalized, efficient, and accurate analysis plan. With advanced instruments and rigorous analysis processes, we commit to providing the highest level of service quality for each project. Welcome to consult for free and learn more details!
Bilingual Project Report
In the technical report, BTP will provide you with a detailed bilingual technical report in both Chinese and English, which includes:
1. Experimental steps (in Chinese and English)
2. Relevant mass spectrometry parameters (in Chinese and English)
3. Detailed information on HCP qualitative identification and relative quantitative analysis
4. Mass spectrometry images
5. Raw data
HCP Qualitative Identification and Relative Quantitative AnalysisOne-Stop Service
You only need to place an order and send the samples
BTP's one-stop service completes: sample processing - on-machine analysis - data analysis - project report
Related Services
Host Cell Protein Residue (HCP) Analysis Service
Protein Mass Spectrometry Identification
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