How to calculate the amino acid composition features, dipeptide composition features, and pseudo amino acid composition features based on the peptide amino acid sequence?
I. Amino Acid Composition (AAC)
1. Principle
Calculate the relative frequency of the 20 standard amino acids in a sequence.
2. Calculation Formula
Figure 1
II. Dipeptide Composition (DPC)
1. Principle
Calculate the frequency of all 400 possible dipeptides (AA, AC, ..., YY) to capture local sequence order information of amino acids.
2. Calculation Formula
Figure 2
III. Pseudo Amino Acid Composition (PseAAC)
1. Principle
Introduce physicochemical properties of amino acids (such as hydrophobicity, polarity, side chain mass, etc.) and sequence order-related information based on AAC, commonly used in machine learning modeling.
2. Basic Form (Type I)
Figure 3
Biotech-Pack Biosciences - A leading service provider for characterization of biological products, offering high-quality mass spectrometry detection for multi-omics studies.
Related Services:
How to order?
