Triglycerides (triacylglycerol, TAG) are esters derived from glycerol and three fatty acid molecules. The simplest triglycerides are those in which all three fatty acids are the same. The length of the fatty acids attached to glycerol can range from 4 to 24 carbons, but the most common are 16, 18, and 20 carbons. Fatty acids can be saturated or unsaturated. Naturally occurring fatty acids in plants and animals typically consist of an even number of carbon atoms because they are biosynthesized from two-carbon units of acetyl-CoA. Bacteria have the ability to synthesize odd-numbered carbon branched-chain fatty acids.
A Triglyceride
Most naturally occurring fats contain different triglycerides. In the intestine, triglycerides are broken down into monoacylglycerol and free fatty acids during lipolysis. The liver is the primary organ for synthesizing and storing triglycerides. When the body needs fatty acids as an energy source, the hormone glucagon triggers the breakdown of triglycerides via hormone-sensitive lipase, releasing free fatty acids to provide energy for the body. Since the brain cannot directly utilize fatty acids, the glycerol part of triglycerides needs to be converted into glucose through gluconeogenesis to serve as fuel for the brain. Elevated levels of TAGs in humans have been associated with various diseases, including atherosclerosis, heart disease, stroke, and metabolic syndrome. However, the exact negative impacts of elevated TAGs levels are not well understood.
BiotechPack provides reliable, fast, and cost-effective triglyceride TAGs analysis services based on highly stable, reproducible, and sensitive systems for separation, characterization, identification, and quantitative analysis, combined with LC-MS.
BiotechPack offers the following triglyceride TAGs analyses
