Proteomics and Metabolomics
Proteomics and metabolomics are disciplines that study proteomes and metabolomes, respectively. Joint analysis of proteomes and metabolomes helps to study the life activities of organisms more deeply. Biotech company BGI provides mass spectrometry-basedproteomicsandmetabolomicsanalysis services.
Proteomics and metabolomics
Omics is a holistic study of the rules of life activities in organisms, studying an organism, a cell, or a tissue from a comprehensive perspective. Omics research began with genomics, and proteomics and metabolomics are disciplines that emerged in the post-genomics era. Proteomics refers to large-scale studies of the characteristics of protein macromolecules at an overall level, including protein expression levels, post-translational modifications, and protein-protein interactions. Metabolomics refers to large-scale studies at an overall level of small molecules in organisms, cells, or tissues, including the identification of metabolites, analysis of expression levels, and their interaction analysis. Both proteomics and metabolomics can be applied in various fields, such as disease diagnosis, pharmaceutical research and development, nutritional food science, toxicology, environmental science, and botany. Proteomes and metabolomes can be analyzed and detected using liquid chromatography and mass spectrometry techniques.
Joint analysis of proteomics and metabolomics
Compared with single omics research, multi-omics joint analysis can more comprehensively and deeply explore the mechanisms and principles of life activities. For example, combining proteomics analysis with metabolomics analysis, where metabolomics can provide information for the functional interpretation of proteomics data, while proteomics analysis can highlight the participating enzymes or enzymatic pathways to help better understand metabolomics data. The combination of proteomics and metabolomics helps elucidate the molecular mechanisms of various diseases, including cancer, mental disorders, and cardiovascular diseases.
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Proteomics and Metabolomics
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