What are the advantages and disadvantages of label-free quantitative technology?

The advantage of label-free is that it does not require labeling, making it simple to operate, cost-effective, and not limited by sample size. However, its downside is that label-free quantification accuracy is not as good as labeled quantification. It also demands high performance from mass spectrometers and requires stability and repeatability in experimental operations.

• Quantitative Proteomics Analysis Based on Label-Free