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百泰派克蛋白质测序
百泰派克蛋白质组学服务
百泰派克生物制药分析服务
百泰派克代谢组学服务

AAE-2D Antibody Coverage Analysis

In the process of biologic drug manufacturing, residual host cell proteins (HCPs) are a quality control issue that cannot be ignored. These residual proteins can potentially affect the safety, stability, and bioactivity of the drug. Therefore, precise and comprehensive analysis of HCPs is crucial. Affinity Antibody Extraction-Two Dimensional electrophoresis (AAE-2D) is a combined technique mainly used for efficient detection and analysis of proteins. It combines the affinity enrichment capability of antibodies with the separation efficiency of two-dimensional electrophoresis to achieve in-depth analysis of complex protein samples. AAE-2D technology utilizes antibody affinity enrichment to effectively capture target HCPs, followed by in-depth identification and quantification through two-dimensional electrophoresis. This allows for comprehensive coverage of HCPs by antibodies, enabling accurate assessment of antibody coverage, particularly suitable for analysis of antibody coverage for residual host proteins.

 

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Antibody Affinity Enrichment (AAE) Technology

 

Biotyech Park Biotechnology (BTP) has passed CNAS/ISO9001 dual quality system certification. The company has developed an efficient AAE-2D antibody coverage analysis platform utilizing high-resolution electrophoresis equipment, committed to providing you with the most advanced HCP antibody coverage analysis services. This service is particularly suitable for quality control of complex biologics such as recombinant proteins, antibody drugs, fusion proteins, as well as gene and cell therapies. Our analysis can not only identify the types and amounts of HCPs but also evaluate their distribution and potential impact in biologic drugs, thus providing scientific basis for your drug development and production processes. We welcome you to consult us for more details.

 

Bilingual Project Report (Chinese/English)

In the technical report, Biotyech Park will provide you with a detailed bilingual (Chinese and English) version of the technical report, including:

1. Experimental Procedures (Chinese and English)
2. Relevant Experimental Parameters (Chinese and English)
3. Detailed Information on AAE-2D Antibody Coverage Analysis
4. Electrophoresis Images
5. Raw Data

 

AAE-2D Antibody Coverage AnalysisOne-Stop Service

You only need to place an order and send samples
Biotyech Park completes the one-stop service: sample processing, on-machine analysis, data analysis, and project report

 

Related Services

Host Cell Protein (HCP) Analysis Services

Biopharmaceutical Analysis 

Antibody-Drug Conjugates (ADCs) Analysis

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