Metabolomics and 16S rDNA Sequencing Integrated Analysis
Metabolomics is a large-scale study of small molecules (commonly referred to as metabolites) within cells, biofluids, tissues, or organisms. 16S rDNA is the gene encoding 16S rRNA, present in all bacterial genomes. 16S rDNA can reflect differences between different genera of bacteria and can be easily sequenced using sequencing technologies. It is widely used for the detection and identification of pathogens, as well as the phylogenetic classification of different microbial communities at the genus or species level. Integrating analysis of 16S rDNA sequencing data and metabolomics data can reveal the associations between specific microbial communities and specific metabolites, and identify key strains that cause changes in the metabolic state or functional small molecule metabolites of the community. Moreover, studying the relationship between metabolites-microbes-diseases through integrated analysis of metabolomics and 16S rDNA sequencing can help discover biomarkers for diseases, which can be further applied in clinical auxiliary diagnosis. For example, the study of the relationship between gut microbiota and host metabolic phenotype and how microbial communities affect metabolic functions is a typical case of integrating metabolomics and 16S rDNA sequencing results.
BiotechPack Bioinformatics Co., Ltd. offers targeted and untargeted metabolomics analysis services for a variety of samples based on techniques such as GC-MS, LC-MS, and NMR, combined with 16S rDNA sequencing services. By integrating customizable bioinformatics analysis methods, BiotechPack provides one-stop metabolomics and 16S rDNA sequencing integration analysis service from experimental design, sample detection, to data analysis, meeting various detection needs.
Metabolomics and 16S rDNA Sequencing Integration Analysis Workflow
Metabolomics and 16S rDNA Sequencing Integration Analysis Workflow
Application Fields
Agriculture and Forestry: Mechanisms of stress resistance, species protection research, etc.
Animal Husbandry: Pathogenic mechanism research, meat and dairy product quality research, etc.
Marine Fisheries: Fishery environment and seafood safety, etc.
Microbiology: Pathogenic mechanisms, drug resistance mechanisms, pathogen-host interaction research, etc.
Biomedicine: Biomarkers, disease mechanisms, disease classification, drug development, personalized treatment, etc.
Environmental Science: Optimization of fermentation processes, biofuel production, environmental hazard risk assessment research, etc.
Food Science: Optimization of food storage and processing conditions, food component and quality identification, food safety monitoring, etc.
Bilingual Project Report (Chinese/English)
In the technical report, BiotechPack will provide you with a detailed bilingual (Chinese/English) technical report, including:
1. Experimental Procedures (Chinese and English)
2. Relevant Experimental Parameters (Chinese and English)
3. Mass Spectrometry Images
4. Raw Data
5. Metabolomics and 16S rDNA Sequencing Results
Case Interpretation
Related Services
Transcriptomics and Metabolomics Integrated Analysis
Proteomics and Metabolomics Integrated Analysis
Post-translational Modification Proteomics and Metabolomics Integrated Analysis
Metabolomics
16S/18S/ITS Full-length Sequencing
16S/18S/ITS Amplicon Sequencing
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