Protein Oxidation Modification Analysis
Protein oxidation modifications are typically caused by reactive oxygen species (ROS) such as superoxide anions, hydrogen peroxide, hydroxyl radicals, etc. These ROS can be generated in organisms through various pathways, including mitochondrial respiration, enzyme-catalyzed redox reactions, radiation, and more. While protein oxidation modifications are a normal physiological process, excessive production of ROS or reduced clearance can lead to excessive protein oxidation, affecting their function and potentially causing cellular damage.
With the advancement of molecular biology and biochemistry techniques, protein mass spectrometry has become a major tool for studying protein oxidation modifications. Mass spectrometry can accurately identify the oxidatively modified amino acid residues and their chemical structures, thereby exploring the types and mechanisms of protein oxidation modifications in depth. By using mass spectrometry, we can high-throughput screen and quantitatively analyze the oxidation modification sites of proteins, providing important information for understanding the mechanisms of oxidative stress response and related diseases.
Lin, Y. S. et al. Anal. Chem. 2019.
Mass Spectrometry Analysis of Protein Oxidation Modifications
Biotech Pack (BTP) has been certified by dual quality systems CNAS/ISO9001. The company has developed and validated a high-precision protein oxidation modification analysis method based on Thermo's Orbitrap Fusion Lumos mass spectrometer combined with Nano-LC nanoscale chromatography technology. This method can perform quantitative and qualitative analysis of protein oxidation modifications, providing precise location and modification type information. We accept different protein samples and offer a free customized one-stop solution according to customer needs to meet various research requirements. Free consultations are welcome!
Chinese/English Project Report
In the technical report, Biotech Pack will provide you with a detailed bilingual (Chinese and English) technical report, including:
1. Experimental procedures (Chinese and English)
2. Related experimental parameters (Chinese and English)
3. Detailed information on protein oxidation modifications
4. Mass spectrometry images
5. Raw data
BiotechPack, A Biopharmaceutical Characterization and Multi-Omics Mass Spectrometry (MS) Services Provider
You only need to place an order and send samples
Biotech Pack's one-stop service completion: sample processing - on-machine analysis - data analysis - project report
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