Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a typical systemic autoimmune disease characterized by the loss of self-immune tolerance and the production of high levels of self-reactive antibodies against self-antigens, leading to organ damage. This process involves multiple cytokines. Numerous studies have investigated the expression and role of CD40L (CD154) in SLE, as its expression appears to be significantly increased. In both human and mouse model systems, the long-term expression of CD40L is found in lupus T cells, which may lead to excessive B cell activation and, in turn, the pathogenesis of the disease. Elevated levels of soluble CD30 in SLE serum are a marker for disease activity assessment. IL-10, as a prominent Th2 cytokine, has also been shown to play a role in this autoimmune disorder. Additionally, IL-13 has been a focus of SLE research. The increase in pro-inflammatory cytokines such as IL-6, IL-12, IL-18, and TNF α may trigger the inflammatory process of SLE. All these markers have been found to be increased in SLE patients and are associated with disease activity. Elevated levels of interferon α in the serum of active SLE patients have been well known, specifically, the vesicle inclusion within renal vascular endothelial cells of systemic lupus erythematosus patients is induced by interferon α.

Systemic Lupus Erythematosus - Flow Cytokine Detection

Biotech Pack uses flow cytometry to simultaneously quantitatively detect cytokines and proteins related to systemic lupus erythematosus disease, providing higher sensitivity and a wider detection range. The table below lists the cytokines detectable in human samples, and Biotech Pack also offers detection for other species. Welcome to inquire.

Systemic Lupus Erythematosus - Flow Cytokine Detection Indicators

Systemic Lupus Erythematosus Human Sample Multiplex Flow Kit

Systemic Lupus Erythematosus Human Sample Single Factor Flow Kit

About the Sample

1. Only 25µL of sample is needed, while conventional ELISA requires 50µL or 100µL of sample.
2. Suitable for serum, plasma, cell culture supernatant, and various body fluids.
3. Body fluid samples are stored in a -80°C freezer and transported with dry ice.

Chinese/English Project Report:

In the technical report, Biotech Pack will provide you with a detailed bilingual (Chinese and English) technical report, which includes:

1. Experimental Procedures (Chinese and English)
2. Raw Data (Fluorescence Emission Spectrum)
3. Technical Report
4. Absolute Content of Each Detection Index (Excel Spreadsheet)

Flow Multiplex Detection One-stop Service

You only need to place an order - send the sample

Biotech Pack's one-stop service completion: Sample Processing - Machine Analysis - Data Analysis - Project Report

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