Exosome Sequencing

Exosomes function in intercellular communication and signal transductionarea type of extracellular vesicle.Exosome sequencing primarily involves sequencing RNA within exosomes,including messenger RNA (mRNA), microRNA (miRNA), long non-coding RNA (lncRNA), etc.These RNAs play important roles in gene expression regulation, cellular functions, and biological processes. Exosome sequencing allows researchers to gain deep insights into the mechanisms of intercellular communication and the roles of exosomes in physiological and pathological processes.Since1983when exosomes were first described, exosome sequencing technology has continuously developed and improved, providing crucial information for diagnostics, prognostic treatment, and the discovery of therapeutic targets.

BaiTaiPaiKe Biotechnology offers a one-stop exosome sequencing service based on the Illumina high-throughput sequencing platform, capable of detecting the overall transcription level of any exosome at the single-nucleotide level. While analyzing transcript structure and expression levels, it can also discover unknown and rare transcripts and accurately identify alternative splicing sites and coding sequence single nucleotide polymorphisms (cSNPs), thereby providing the most comprehensive transcriptome information.

BaiTaiPaiKe BiotechnologyExosome SequencingGeneral Process

1.Exosome Isolation

2.RNA Extraction and Purification

3.Sample Quality Control

4.Library Construction

5.High-Throughput Sequencing

6.Data Analysis

Exosome SequencingTechnical Advantages

1.Experienced technicians providing comprehensive professional services from experimental design, sample testing, to data analysis;
2.Clear processes to reduce unnecessary waste of samples and time, resulting in short delivery times;
3.BaiTaiPaiKe Biotechnology possesses an independent bioinformatics analysis platform, capable of providing advanced customized analysis in addition to routine analysis;
4.BaiTaiPaiKe's proteomics, metabolomics, and other multi-omics analysis platforms can perform integrated multi-omics analysis, enhancing publication quality.

Exosome SequencingTechnical Applications

1.Biomarker Discovery

In fields like cancer, neurodegenerative diseases, and cardiovascular diseases, researchers have successfully utilized exosome sequencing technology to identify biomarkers with diagnostic and predictive value.

2.Intercellular CommunicationResearch

Exosomes facilitate communication between cells by transmitting signaling molecules, and exosome sequencing technology enables the study of these signaling molecules to gain deep insights into the mechanisms of intercellular communication.

3. Drug Delivery Systems

Exosomes are often used as drug delivery carriers to enhance the therapeutic effect of drugs and reduce side effects. Exosome sequencing technology helps study the behavior and mechanisms of drugs within exosomes.

4. Tumor Microenvironment Research

Exosomes can alter the behavior of cells surrounding tumors, promoting tumor development. Exosome sequencing technology provides better understanding of the tumor microenvironment and the role of exosomes within it.

About Samples

Sample Types	Cell Culture Media	Tissue Samples	BloodFluid	Urine	Breast Milk	Saliva
Sample Quantity	10-50ml	10-100ml	1-5ml	10-100ml	1-5ml	1-5ml

One-Stop Exosome Sequencing Service

You only need to place an order and send samples
BaiTaiPaiKe's one-stop service completes: sample processing, on-machine analysis, data analysis, and project reporting

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