Antibody Sequence Analysis

Antibodies are immunoglobulins composed of four polypeptide chains that can specifically bind to antigens. They play a very important role in the body's immune system, such as clearing various pathogenic microorganisms, viruses, and parasites that invade the body, and maintaining the body's balance. Some antibodies can synthesize various antibody drugs in vitro, such as monoclonal antibodies, as a means of disease treatment. Therefore, the information of the antibody amino acid sequence is undoubtedly a necessary prerequisite for antibody synthesis.

The essence of an antibody is an immunoglobulin, and antibody sequence analysis is the identification of the amino acid sequence that makes up the antibody polypeptide. The analysis methods and principles are similar to those of protein sequence analysis, mainly using mass spectrometry-based methods combined with biological information analysis to identify the full-length sequence or variable region amino acid sequence of antibodies.

Biotech company Baitai Parker has established a new generation antibody sequencing platform based on high-resolution Obitrap Fusion Lumos mass spectrometer combined with rich bioinformatics analysis experience, providing fast and accurateantibody sequence analysistechnical services. It can perform sequence analysis on different subtypes of antibodies (such as IgG and IgM) and different types of antibodies (fluorescently labeled antibodies, immobilized antibodies, antibodies from different species), including the full-length sequence and variable region amino acid sequence of antibodies. Free consultation is welcome.

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