The extracellular polymeric substances (EPS) obtained contain proteins, polysaccharides, lipids, etc. Can mass spectrometry determine the specific proteins in EPS and their amino acid sequences?

Of course! Mass spectrometry (especially tandem mass spectrometry, also known as MS/MS) is a very powerful tool and a core technology in the field of proteomics research. It is widely used in the qualitative and quantitative identification of proteins, identification of post-translational modifications, and amino acid sequence identification. It is recognized in the industry for its high precision, high throughput, and high accuracy. If you want to identify the types of proteins and their amino acid sequences in extracellular polymeric substances (EPS), mass spectrometry is your method of choice!

Biotech-Pack uses the latest Obitrap Fusion Lumos mass spectrometer from Thermo combined with Nano-LC nanoscale chromatography technology to provide efficient and accurate protein mass spectrometry identification services for protein extracts, SDS-PAGE protein bands, 2D protein spots, pull-down, and Co-IP samples.

Biotech-Pack proteomics mass spectrometry identification schematic

In addition, our company uses nano LC-MS/MS nanoscale chromatography combined with tandem mass spectrometry and Shimadzu's Edman degradation sequencing system to analyze protein sequences. We offer mass spectrometry-based protein sequencing analysis services, including amino acid composition analysis, N-terminal sequencing, C-terminal sequencing, and full sequence analysis, as well as Edman degradation-based protein N-terminal sequence analysis services. For proteins with unknown theoretical sequences, we provide de novo sequencing services to analyze protein sequences.