Oligonucleotide Sequence Analysis

Oligonucleotide sequence analysis is a biotechnology used to study and determine the types and arrangement of nucleotides in short DNA or RNA fragments (usually 20-30 nucleotides). It has significant application value in many fields of biology and medicine. Oligonucleotides are a new hot spot in drug research, and some oligonucleotides that specifically bind or cleave pathogenic genes can be developed into novel drugs. They are efficient, have a wide range of applications, and can supplement traditional drugs, showing broad application prospects. Sequence analysis of oligonucleotides is an essential step in the research and production of gene drugs.

BTP-Oligonucleotide Sequence Analysis Process

The development of mass spectrometry technology provides a powerful analytical method for oligonucleotide sequence identification. Oligonucleotide molecules are dissociated into a series of fragment ions in a high-resolution mass spectrometer, and these fragments carry mass-to-charge (m/z) values. By analyzing these fragment ions, the base sequence of the original oligonucleotide can be deduced. Biotech company BTP, certified by CNAS/ISO9001, has developed and validated a high-precision oligonucleotide sequence analysis method based on Thermo's Orbitrap Fusion Lumos mass spectrometer combined with Nano-LC chromatography technology. This method can perform high-resolution, high-accuracy sequence identification of various oligonucleotide samples such as ASOs (antisense oligonucleotides), siRNA (small interfering RNA), miRNA (microRNA), and Aptamers (nucleic acid aptamers), meeting different customer needs.

Bilingual Project Report (Chinese/English)

In the technical report, BTP will provide you with a detailed bilingual technical report in both Chinese and English, including:

1. Experimental procedures (Chinese and English)
2. Relevant mass spectrometry parameters (Chinese and English)
3. Detailed information on oligonucleotide sequence analysis
4. Mass spectrometry images
5. Raw data

Oligonucleotide Sequence AnalysisOne-stop Service

You only need to place an order and send samples
BTP's one-stop service completes: sample processing - on-machine analysis - data analysis - project report

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