Modified Proteomics Types and Applications
Protein modification proteomics is a new research field developed from proteomics, mainly focusing on changes that occur to proteins post-translation through the addition or removal of chemical groups. Protein modification proteomics can be divided into phosphorylation proteomics, acetylation proteomics, ubiquitination proteomics, methylation proteomics, glycosylation proteomics; protein modification proteomics; protein modification proteomics has broad applications in life sciences, medical research, drug development, and other fields.
1. Types of Protein Modification Proteomics
Generally, protein modification proteomics can be divided into the following categories:
1. Phosphorylation Proteomics
Phosphorylation is one of the most common post-translational modifications of proteins, having significant effects on cell signaling, protein-protein interactions, and more.
2. Acetylation Proteomics
Acetylation mainly occurs at the N-terminus of proteins and plays a regulatory role in protein stability, localization, and more.
3. Ubiquitination Proteomics
Ubiquitination mainly involves the formation of covalent bonds between ubiquitin proteins and target proteins, affecting protein stability, activity, and so on.
4. Methylation Proteomics
Methylation can alter the charge properties of proteins, influencing their functions.
5. Glycosylation Proteomics
Glycosylation is an important biological modification that affects protein secretion, stability, immune response, and more.
2. Applications of Protein Modification Proteomics
Protein modification proteomics has broad applications in life sciences, medical research, drug development, and other fields, such as:
1. Disease Diagnosis and Treatment
Studying the post-translational modifications of proteins can help identify protein markers associated with specific diseases, used for early diagnosis and treatment.
2. Drug Development
Post-translational modifications of proteins significantly impact protein function, making them important targets for drug development.
3. Biotechnology
Post-translational modifications can also be used to produce proteins with specific functions, such as industrial enzymes, biopharmaceuticals, etc.
BiotechPack, A Biopharmaceutical Characterization and Multi-Omics Mass Spectrometry (MS) Services Provider
Related Services:
Tyrosine Phosphorylation Quantitative Proteomic Analysis
Multi-pathway Phosphorylation Proteomics
Post-translational Modification Proteomic Analysis
How to order?
